Use of stem cells in bone regeneration in cleft palate patients: review and recommendations
Amiri Mohammad Amin, Lavaee Fatemeh, Danesteh Hossein,
소속 상세정보
( Amiri Mohammad Amin ) - Shiraz University of Medical Sciences Student Research Committee
( Lavaee Fatemeh ) - Shiraz University of Medical Sciences School of Dentistry Department of Oral and Maxillofacial Medicine, School of Dentistry
( Danesteh Hossein ) - Shiraz University of Medical Sciences School of Dentistry Department of Oral and Maxillofacial Surgery
Abstract
This study was conducted to review the efficacy of different sources of stem cells in bone regeneration of cleft palate patients. The majority of previous studies focused on the transplantation of bone marrow mesenchymal stem cells. However, other sources of stem cells have also gained considerable attention, and dental stem cells have shown especially favorable outcomes. Additionally, approaches that apply the co-culture and co-transplantation of stem cells have shown promising results. The use of different types of stem cells, based on their accessibility and efficacy in bone regeneration, is a promising method in cleft palate bone regeneration. In this regard, dental stem cells may be an ideal choice due to their efficacy and accessibility. In conclusion, stem cells, despite the lengthy procedures required for culture and preparation, are a suitable alternative to conventional bone grafting techniques.
키워드
Cleft palate; Tissue engineering; Bone regeneration; Craniofacial abnormalities; Stem cells
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